resilience experiments

LSD Microdosing

LSD is short for d-lysergic acid diethylamide, a compound discovered by Albert Hoffman in the 1940s which he created by slightly changing a natural molecule found in a type of fungi (ergot fungus).     So technically it is not ‘natural’ although it is derived from a chemical in nature so some consider it ‘semi-synthetic and sometimes it is considered to be in a similar category as ‘plant medicine’ compounds such as DMT and psilocybin.    LSD in classic ‘tripping’ on hallucinogenic doses produces a psychedelic experience, often known as a ‘trip’ which is highly individual but generally involves dramatic changes in perception in multiple ways, where how you think, see and feel can be dramatically different which lasts up to 12-16 hours.  However, in more recent years, LSD has been a substance increasingly used as a self-development substance in very tiny quantities, which are very small indeed for LSD since ‘classic psychedelic doses are still in the microgram range (25+ micrograms).  

The definition of ‘micro-dosing of psychedelics is taking sub-perceptual (Eg. unnoticeable) amounts of a psychedelic substance below the dose which changes your perception of reality or causes you to ‘trip’ or hallucinate, or anything close to this.  In fact, if you are trying to microdose and notice any substantial change in perception, you have gone beyond a microdose into a small ‘classic’ dose and would need to lower the dose further to get into the microdose range.  Reasons people have tried microdosing include help with mood, depression, or anxiety, focus, and creative problem-solving abilities, improve energy, enhance their EQ, and generally helping them feel better and happier in daily life.   Some small recent studies have shown that contrary to previous belief, microdosing is not a placebo and does have biological effects.  

With LSD, a typical microdose usually starts between 5-10ug per day, with many dosing schedules being every 3 days to prevent tolerance, since taking LSD every day even in microdose amounts decreases its effect over time without taking breaks of a few days in between doses. 

Risks & Cautions: LSD is illegal in many countries outside of a research context.  It is currently not considered addictive.  The adverse effects of a ‘bad trip’ possible with larger doses do not necessarily apply to microdoses.  The risk of a microdose triggering a psychotic episode is probably even lower than the very low risk seen with classic doses but caution may be warranted in those with a personal or close relative family history of a psychotic condition. The long-term effects of microdosing regularly with LSD are not studied or reported yet in the research.